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Obesity as a risk factor for complications and mortality in individuals with SARS-CoV-2: A systematic review

dc.contributor.authorde Paula Silva Lalucci, Marielle Priscila
dc.contributor.authorde Souza Marques, Déborah Cristina
dc.contributor.authorValdés-Badilla, Pablo
dc.contributor.authorVidal Andreato, Leonardo
dc.contributor.authorMagnani Branco, Braulio
dc.date.accessioned2024-04-16T19:19:46Z
dc.date.available2024-04-16T19:19:46Z
dc.date.issued2024
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/5313
dc.description.abstractThis systematic review aimed to analyze the available studies that identified overweight and/or obesity as a risk factor for mortality, use of respiratory support, and changes in biochemical markers in adults hospitalized with SARS-CoV-2. The PubMed, Web of Science, and Scopus databases were searched using PRISMA guidelines until January 2024. The protocol was registered with PROSPERO (code: CRD42024501551). Of the 473 articles, only 8 met the inclusion criteria (e.g., adult individuals aged 18 or over diagnosed with COVID-19 individuals with overweight and/or obesity). In addition, the Downs and Black tool was used to assess the quality of the studies. The studies analyzed totaled 9782 adults hospitalized for COVID-19, indicating that overweight and obesity are present in more than half of adults. Diseases such as diabetes mellitus and hypertension are more prevalent in adults with obesity. The systematic review also highlighted that a higher incidence of respiratory support is related to a higher incidence of hospitalization in intensive care units and that adults with overweight and obesity have a higher risk of mortality from COVID-19. Biochemical markers such as procalcitinin, C-reactive protein, and interleukin-6 are associated with the severity of COVID-19 infection. This systematic review exposed overweight and/or obesity as a risk factor for worse COVID-19 disease, as well as for the need for intensive care, respiratory support, mortality, and changes in essential blood markers.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceNutrients, 16(4), 543es_CL
dc.subjectCOVID-19es_CL
dc.subjectOvernutritiones_CL
dc.subjectHospitalizationes_CL
dc.subjectOxygen inhalation therapyes_CL
dc.subjectClinical laboratory techniqueses_CL
dc.titleObesity as a risk factor for complications and mortality in individuals with SARS-CoV-2: A systematic reviewes_CL
dc.typeArticlees_CL
dc.ucm.facultadFacultad de Ciencias de la Educaciónes_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.urimdpi.com/2072-6643/16/4/543es_CL
dc.ucm.doidoi.org/10.3390/nu16040543es_CL


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