Ver publicación 

Mostrar el registro sencillo de la publicación

Covid-19 in hospitalized kidney transplant recipients: analysis of the multicenter registry during the first wave of the pandemic in Chile

dc.contributor.authorPefaur, J
dc.contributor.authorToro, L.
dc.contributor.authorBadilla, X
dc.contributor.authorArdiles, L.
dc.contributor.authorBoltansky, A
dc.contributor.authorRosatti, P
dc.contributor.authorTapia, B
dc.contributor.authorRocca, X
dc.contributor.authorMur, P
dc.contributor.authorFernández, A
dc.contributor.authorCastillo, Á
dc.contributor.authorDíaz, C
dc.contributor.authorElgueta, L
dc.contributor.authorGarcía, F
dc.contributor.authorMüller, H
dc.contributor.authorMansilla, R
dc.contributor.authorMuñoz, C
dc.contributor.authorSalvatici, M
dc.contributor.authorEsperanza, SM
dc.contributor.authorValenzuela, M
dc.contributor.authorZamora, D
dc.contributor.authorEnciso, G
dc.contributor.authorPanace, R
dc.contributor.authorCabrera, S
dc.contributor.authorOrtiz, AM
dc.contributor.authorMardones, S
dc.contributor.authorOshiro, C
dc.contributor.authorSánchez, J.E
dc.contributor.authorLorca, E
dc.contributor.authorTorres, R
dc.date.accessioned2024-09-10T13:34:20Z
dc.date.available2024-09-10T13:34:20Z
dc.date.issued2024
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/5653
dc.description.abstractIntroduction: The severity of COVID-19 infection in kidney transplant patients has been well-documented. Objectives: This study aims to determine the epidemiological and clinical data and identify predictors of poor prognosis during the epidemic’s early stages. Material and methods: This is a national semi-prospective, multicenter study of subjects with functioning grafts who were infected during the first wave of the pandemic in Chile between March 1 and September 31, 2020. Results: during this period, we recorded the hospitalization of 97 adult patients throughout the entire national territory. The average age was 52.5 years, 62% men, 45% hypertensive, 11% coronary, 10% diabetic, and 5% with chronic obstructive pulmonary disease, with an average post-transplant follow-up of 7.2 years and an average previous renal function of 47.7ml/min/1.7m2 (CKD-EPI formula). Between the onset of symptoms and diagnosis, there was an average period of 4.8 days, with a predominance of cough (44%), dyspnea (42%), and fever (42%). 34% developed acute kidney injury, and 36% of them required dialysis support. The lethality was 30%, prevailing in those with multiple organ failure (80%) and those who required invasive mechanical ventilation (52%). In the multivariate analysis, the best predictors of mortality were older age (OR: 2.92) and living in a low-income commune (OR: 2.35). Conclusions: This national project of the Chilean Society of Nephrology provided valuable information for monitoring the epidemiological evolution of the pandemic. It also helped to propose priority vaccination strategies, adjust immunosuppressive therapy, and design logistical aspects to reduce the risks for transplant patients.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceRevista de Nefrología, Diálisis y Trasplante, 44(2), 91-98es_CL
dc.subjectPandemices_CL
dc.subjectKidney Transplantationes_CL
dc.subjectCOVID-19es_CL
dc.subjectMortalityes_CL
dc.subjectChilees_CL
dc.subjectSyndemices_CL
dc.titleCovid-19 in hospitalized kidney transplant recipients: analysis of the multicenter registry during the first wave of the pandemic in Chilees_CL
dc.typeArticlees_CL
dc.ucm.facultadFacultad de Medicinaes_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.urimedigraphic.com/cgi-bin/new/resumenI.cgi?IDARTICULO=117034es_CL


Ficheros en la publicación

FicherosTamañoFormatoVer

No hay ficheros asociados a esta publicación.

Esta publicación aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo de la publicación

Atribución-NoComercial-SinDerivadas 3.0 Chile
Excepto si se señala otra cosa, la licencia de la publicación se describe como Atribución-NoComercial-SinDerivadas 3.0 Chile